A COMPARATIVE STUDY OF SOFT-SENSING METHODS FOR FED-BATCH FERMENTATION PROCESSES
نویسندگان
چکیده
منابع مشابه
A Comparative Study of Soft-sensing Methods for Fed- Batch Fermentation Processes
A comparative study of software sensors using Multiway Partial Least Squares and Extended Kalman Filters in an application to a fed-batch yeast fermentation process is presented. The MPLS theory is introduced firstly and then applied to a yeast fed-batch fermentation process to provide soft-sensing facilities. The soft-sensing capabilities of the MPLS approach are found to compare favourably wi...
متن کاملIntelligent Software Sensors for Fed-Batch Fermentation Processes
Software sensors have attracted great research interests due to the problem of lacking suitable and robust online sensors for key fermentation variables in fed-batch fermentation processes. In this paper, intelligent software sensors have been developed based on multivariate statistical process control methods. The software sensors not only provide real time estimation of key variables but also...
متن کاملEvolutionary Algorithms for Optimal Control in Fed-Batch Fermentation Processes
In this work, Evolutionary Algorithms (EAs) are used to achieve optimal feedforward control in a recombinant bacterial fed-batch fermentation process, that aims at producing a bio-pharmaceutical product. Three different aspects are the target of the optimization procedure: the feeding trajectory (the amount of substrate introduced in a bioreactor per time unit), the duration of the fermentation...
متن کاملOptimal Adaptive Control of Fed-batch Fermentation Processes
This paper presents a unifying methodology for optimization of biotechnological processes, namely optimal adaptive control, which combines the advantages of both the optimal control and the adaptive control approaches. As an example, the design of a substrate feeding rate controller for a class of biotechnologlcal processes in stirred tank reactors characterized by a decoupling between biomass ...
متن کاملModelling of a Fed-Batch Fermentation Process
This report describes the building of a simulator for prediction of the dissolved oxygen concentration, the oxygen transfer rate and the concentration of carbon dioxide in a fermentation process. The steady state models were made using the linguistic equations method. The dynamic models were made using Simulink ® toolbox in the Matlab ® . At the beginning, some basics about fermentation and mic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IFAC Proceedings Volumes
سال: 2005
ISSN: 1474-6670
DOI: 10.3182/20050703-6-cz-1902.02213